I recently rode in the Alzheimer’s Breakthrough Ride, a cross-country relay to raise awareness about Alzheimer’s disease. I rode in the leg from Madison to Chicago on September 1-2. What follows are the notes I recently posted on the blog associated with the ride. Alzheimer’s Breakthrough Ride Journal: Madison to Chicago My Breakthrough Ride experience began in mid-April when the winter snows unexpectedly receded from the Minneapolis landscape and I could start training on the [...]
Before I begin to explain my journey from St. Louis, Missouri to Madison, Wisconsin, I would like to tell you a little about myself. I am a graduate student at Boston University School of Medicine in the Department of Anatomy and Neurobiology (finishing up this year – fingers crossed!), and I am conducting my thesis work in the laboratory of Dr. Rudy Tanzi in the Genetics and Aging Research Unit at Massachusetts General Hospital. On [...]
Dear Readers, As readers of this blog will recall, years of research have revealed that ß-amyloid is produced by the cleavage of a very large protein found throughout the body called amyloid precursor protein, or APP, by the enzyme gamma-secretase. An obvious ‘target’ for pharmaceutical intervention would be the development of gamma-secretase inhibitors: Blocking cleavage of APP by gamma-secretase to form amyloid-ß would prevent this abnormal accumulation in the brain, and prevent ß-amyloid from exerting [...]
Just wanted to add to Buck’s blog….. What a wonderful, fantastic, invigorating experience! Thanks, Bruce Lamb for organizing this important event. Sarah Matousek, Oliver Holmes, Stephanie Soscia and I (Team: Boston Bikers) flew to St. Louis on Friday, August 27th in time to meet the Wash U team as they ended their ride at the signing event there. It was great to see familiar faces (Dave and Tracy Holtzman, John Morris, John Cirrito, etc.) and [...]
Welcome to Checking in from the “Field” with Dr. A., a new monthly blog post on Alzheimer’s Insights. For the last 14 years, in addition to evaluating patients at the Rush Memory Clinic, I have been the “MD in the Field” for many of our community based participatory research studies conducted at the Rush Alzheimer’s Disease Center and the Rush Institute for Aging in Chicago, Illinois.
Over the years performing study related home visits or community presentations, [...]