Sep 222010
 
Brain Atrophy and B Vitamins

Brain atrophy involves the loss of neurons. Some degree of atrophy and subsequent brain shrinkage is common with old age, even in people who are cognitively healthy. However, this atrophy is accelerated in people with mild cognitive impairment and even faster in those who ultimately progress from mild cognitive impairment to Alzheimer’s disease. Many factors have been implicated in affecting the rate of brain atrophy, one of which is high levels of an amino acid [...]

Sep 152010
 
The Connection Between Amyloid, Tau and FYN

Readers, Amyloid plaques and neurofibrillary tangles (NFTs) are the two classic hallmarks of Alzheimer’s disease (AD), but the connection between their two respective proteins—beta-amyloid and tau—has remained mysterious. Now, a paper published on July 21 in the prestigious journal Cell details a molecular mechanism that links tau to beta-amyloid toxicity at the synapse. The groundbreaking new study was led by Professor Jürgen Götz and Dr Lars Ittner, based at the University of Sydney. Back in [...]

Aug 262010
 

Dear Readers, The “hippocampal theta rhythm” is a specific type of electrical activity that can be observed in the hippocampus and other brain structures in numerous species of mammals including rodents, rabbits, dogs, cats, bats and marsupials. In the oldest EEG literature dating back to the 1920s, Greek letters such as alpha, beta, theta and gamma were used to classify EEG waves falling into specific frequency ranges, with “theta” generally meaning a range of about [...]

May 102010
 

Readers, Rarely a day goes by when we do not see several news items about the role of neuro-imaging in detecting, treating or monitoring the progression of Alzheimer’s disease. Here are a few comments to bear in mind as you consume the daily press. Magnetic Resonance Imaging (MRI) yields an image of brain structure and will reveal tumors, strokes and (importantly for Alzheimer’s disease) atrophy (or shrinkage) in particular parts of the brain that can [...]

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