Jun 112012

My recent blog entry “Can Coconut Oil Treat Alzheimer’s?” generated a lot of comments with the same question: “Why isn’t the Alzheimer’s Association researching coconut oil?” It’s an excellent question and one I get often about coconut oil and other substances that have been rumored to help people with Alzheimer’s.

At first glance, the answer is simple: we’ve received few, if any proposals specifically studying  coconut oil. However, we have received a little over half a dozen proposals on studies that look at substances derived from coconut oil such as ketones. Most recently, we funded a study in 2010 by David Morgan, Ph.D. from the University of South Florida. Find a summary of his study here: Ketogenesis and Alzheimer Pathology.

In addition, I encourage readers to check out the section of our web site that discusses a research study on Caprylic Acid and Coconut Oil. This substance derived from coconut oil looked promising in early studies but the makers of the supplement opted to stop researching it prior to phase three trials that would have tested effectiveness. We were disappointed they didn’t continue the study.

At the Alzheimer’s Association, we fund mainly studies by new investigators, which helps us encourage the next generation of Alzheimer’s researchers and introduce fresh ideas to the field.

Every year, we receive grant applications through an online proposal process from hundreds of researchers from around the world. Those proposals are then peer reviewed by a panel of three to four volunteer Alzheimer’s research experts and they are scored and ranked. Finally, they are sent to the Alzheimer’s Association Medical and Scientific Advisory Council (MSAC), a group of nationally and internationally recognized Alzheimer’s experts. The MSAC is tasked with ensuring fairness and equity in the peer review process and making recommendations for funding to the Alzheimer’s Association.

Basically, our research dollars go to the research proposals that have the most merit – no matter what the institution or country of origin, we simply want to fund the best designed studies that will get us closer to better treatments, early detection or prevention.

However, while we are the largest private nonprofit funder of Alzheimer’s research, even we cannot fund all of the studies that should be funded. For example, out of the hundreds of research proposals we received in 2011, about 22 percent were found to have merit; but we only had the resources to fund about the top 9 percent. Those studies that don’t get funding from us may find funding elsewhere, or re-apply next year – but in some cases, they fall to the wayside. It’s frustrating to know that the answers may be out there, right within reach but the research funding simply doesn’t exist.

We are working hard on several pieces of legislation right now that will help ensure the future of Alzheimer’s research, including the Breakthrough Act and the HOPE for Alzheimer’s Act. We’re already seeing our work on the National Alzheimer’s Project Act starting to benefit the research community and hope that it continues to do so.

About the  author: Elizabeth Edgerly, Ph.D., is the chief program officer for the Alzheimer’s Association, Northern California and Northern Nevada Chapter. To read more blog posts by Dr. Edgerly, click here.

This post originally appeared on www.alzheimersblog.org.

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May 102012

We’ve received quite a few questions recently about whether or not coconut oil can be used to treat Alzheimer’s disease. This is a topic that comes up often, so I thought it would be helpful to provide some background:

The claim

This theory has to do with substances called ketones. The damage caused by Alzheimer’s disrupts the brain’s ability to use its primary energy source, known as glucose. The brain naturally gets a portion of its energy from ketone bodies when glucose is less available (e.g., during fasting, strenuous exercise and in newborns). Ketones may provide an alternative energy source to the brain’s cells to moderate the damage caused by Alzheimer’s disease. The body produces ketones when it metabolizes coconut oil and similar substances (fatty acids).

Beyond the headline

Unfortunately, there just isn’t any creditable science to support this idea. It is impossible for us to know how well coconut oil does or does not work in Alzheimer’s disease because there have not been rigorous, large-scale research studies done.

The bottom line

Because there haven’t been any large studies to test the effectiveness of coconut oil, we just can’t say whether it really helps people with Alzheimer’s disease. Maybe it does, maybe it doesn’t. I personally suspect that it has little effect on Alzheimer’s symptoms but, to be fair, I haven’t had any family members, friends or clients who’ve tried it.

My rule of thumb is that if the risks and costs are low, you might consider trying it. If the risks or costs are high, don’t chance it. Think about how you would feel if you gave your loved one something and they lost ground and independence as a result.

Some alternative therapies have substantial risk associated with them; be careful and don’t assume that something that is “natural” is safe. If you are considering trying coconut oil, please consult your doctor first to make sure it will do no harm to the person with dementia

About the  author: Elizabeth Edgerly, Ph.D., is the chief program officer for the Alzheimer’s Association, Northern California and Northern Nevada Chapter. To read more blog posts by Dr. Edgerly, click here.

This post originally appeared on www.alzheimersblog.org.

Learn More:


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